Branched-dextran exo-1,2-alpha-glucosidase

Branched-dextran exo-1,2-alpha-glucosidase (EC 3.2.1.115, dextran 1,2-alpha-glucosidase, dextran alpha-1,2 debranching enzyme, 1,2-alpha-D-glucosyl-branched-dextran 2-glucohydrolase) is an enzyme with systematic name (1->2)-alpha-D-glucosyl-branched-dextran 2-glucohydrolase.[1][2] This enzyme catalyses the following chemical reaction

Hydrolysis of (1->2)-alpha-D-glucosidic linkages at the branch points of dextrans and related polysaccharides, producing free D-glucose
Branched-dextran exo-1,2-alpha-glucosidase
Identifiers
EC no.3.2.1.115
CAS no.72840-94-9
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
Search
PMCarticles
PubMedarticles
NCBIproteins

This enzyme does not hydrolyse disaccharides or oligosaccharides containing linear 1,2-alpha-glucosidic linkages.

References

  1. Mitsuishi, Y.; Kobayashi, M.; Matsuda, K. (1979). "Dextran α-1,2-debranching enzyme from Flavobacterium sp. M-73: its production and purification". Agric. Biol. Chem. 43: 2283–2290. doi:10.1271/bbb1961.43.2283.
  2. Mitsuishi Y, Kobayashi M, Matsuda K (August 1980). "Dextran alpha-(1 yields 2)-debranching enzyme from Flavobacterium Sp. M-73. Properties and mode of action". Carbohydrate Research. 83 (2): 303–13. doi:10.1016/s0008-6215(00)84542-5. PMID 7407800.
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